Botulinum toxin (“Botox”) is a neurotoxic protein produced by the bacterium Clostridium botulinum and it has a number of significant therapeutic applications in neurology.
Mechanism of Action
Neurotoxin Effects: Botox works by blocking the release of acetylcholine, a neurotransmitter responsible for triggering muscle contractions.
Muscle Relaxation: By inhibiting nerve signals, Botox causes relaxation of the targeted muscles, which can alleviate symptoms of various neurological disorders.
Research continues into the use of Botox for other conditions, like neuropathic pain and overactive bladder.
The Procedure
Assessment: Prior to Botox injections, a thorough assessment is conducted to determine the suitability and optimal sites for injection.
Injection Process: Botox is injected directly into the affected muscles using a fine needle. The procedure is usually performed in an outpatient setting (in Dr Bolitho’s rooms) and takes only a few minutes.
Duration of Effect: The effects of Botox typically last for 3-4 months, after which repeat injections are required.
Risks and Side Effects
Localised Pain, Swelling, or Bruising: Common at the injection site.
Muscle Weakness:May occur near the injection site.
Spread of Toxin Effects:Rarely, effects of Botox may spread to other parts of the body, causing symptoms like generalised muscle weakness, vision problems, or difficulty breathing.
Allergic Reactions: Rare, but possible.
Advantages
Targeted Treatment: Botox provides relief directly to the affected muscles without systemic side effects.
Reduces Medication Dependence: Offers an alternative for patients who cannot tolerate or do not respond to oral medications.
Botox injections have become an important tool in the treatment of various neurological disorders. They offer targeted relief with a relatively favourable safety profile. However, the treatment is not a cure, and its effectiveness can vary among individuals.
If Botox Injections are a treatment modality you would like to learn more about, please contact our rooms to make a booking.
Get In Touch
Dr Samuel Bolitho is a Sydney Neurologist with sub-specialised training in movement disorders, essential tremor and Parkinson’s Disease. He brings a rare mx of medical, neurological and computational neuroscience expertise to his role, as well as a wealth of experience in biomedical engineering.
